hrp0092p3-87 | Diabetes and Insulin | ESPE2019

Comprehensive Analysis of HLA System Class II DRB1 in Children with Insulin Dependent Diabetes Mellitus in the North Azerbaijan and Iranian Azerbaijan

Ahmadov Gunduz , Noble Janelle , Ogle Graham

Keywords: Human Leukocyte Antigen system, DRB1 allelesDiabetes mellitus is one of the diseases, the genetics of which has been most widely studied. In 40-50 % cases it is connected with Human Leukocyte Antigene system. The major genetic deterninants of this disease are DQ and DR genes "DR3" and "DR4" haplotypes create high risk for diabetes.Insulin dependent diabetes mellitus risk is very high a...